Open AccessPrimary leiomyosarcoma of the mandible
Author(s) -
Saede Atarbashi-Moghadam,
Abbas Khodayari,
Sepideh Mokhtari
Publication year - 2014
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.140915
Subject(s) - desmin , leiomyosarcoma , mandible (arthropod mouthpart) , eosinophilic , sma* , immunohistochemistry , pathology , lesion , cytoplasm , anatomy , soft tissue , medicine , actin , biology , vimentin , microbiology and biotechnology , botany , mathematics , combinatorics , genus
Leiomyosarcoma (LMS) is a malignant soft tissue tumor that exhibits smoothmuscle differentiation. Its occurrence in the oral cavity is exceedingly rare. This article presents a 67-year-old woman with 9-month history of a painful tumoral lesion on the right side of mandible. Tumor was composed of fascicles of spindle-shaped cells with cigar-shaped nuclei and eosinophilic cytoplasm. Immunohistochemistry showed that tumor cells were positive for smooth muscle actin (SMA) and desmin. The findings were consistent with the diagnosis of LMS.