Open AccessAggressive extranodal peripheral T-cell non-Hodgkin′s lymphoma: A rare case report and review
Author(s) -
Pacha Venkat Bagirath,
Jatin Kumar,
Uttara Dasharatha Arvind,
Shailaja Gangula
Publication year - 2014
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.131918
Subject(s) - lymphoma , medicine , non hodgkin's lymphoma , chromosomal translocation , immune system , human immunodeficiency virus (hiv) , lymph , immunology , pathology , biology , gene , biochemistry
Non-Hodgkin's lymphoma (NHL) is primarily a disorder of lymph nodes, when limited primarily to extranodal sites it is referred to as primary extranodal lymphoma and accounts for 24-48% of all cases of NHL. The development of peripheral T-cell lymphoma is poorly understood and is thought to be associated with effector T cells involving chromosomal translocations. It has been suggested by few authors that the continued increased risk for NHL among highly active antiretroviral therapy (HAART)-treated human immunodeficiency virus (HIV)-infected persons may be a reflection of incomplete immune reconstitution and possibly a chronic state of B-cell hyperactivation. Here, we present one such rare case of extranodal NHL in a known HIV patient.