Open AccessBiosafe alternative to xylene: A comparative study
Author(s) -
Amita Negi,
Abhiney Puri,
Rakhi Gupta,
Isha Chauhan,
Rajat Nangia,
Alisha Sachdeva
Publication year - 2013
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.125199
Subject(s) - xylene , group b , staining , wilcoxon signed rank test , group a , h&e stain , medicine , pathology , chemistry , toluene , organic chemistry , mann–whitney u test
Xylene in one of the non-substitutable chemical used in histology laboratories. However, it is known to have many toxic effects. The toxic effects of xylene include heart and kidney injuries, some fatal blood dyscrasia and other less dangerous problems, such as skin erythema, drying, scaling and secondary infections. The exposure and handling of xylene is maximum during deparaffinizing tissue sections.