Open AccessMonostostic fibrous dysplasia with nonspecific cystic degeneration: A case report and review of literature
Author(s) -
Afreen Nadaf,
MB Radhika,
K Paremala,
N. Srinath
Publication year - 2013
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.119765
Subject(s) - fibrous dysplasia , degeneration (medical) , pathology , lesion , medicine , dysplasia , genetic disorder , anatomy , connective tissue , disease
Fibrous dysplasia (FD) has been regarded as a developmental skeletal disorder characterized by replacement of normal bone with benign cellular fibrous connective tissue. It has now become evident that FD is a genetic disease caused by somatic activating mutation of the Gsα subunit of G protein-coupled receptor. Here we report a case of bilateral monostotic FD in a middle-aged female showing a classic histological picture, but radiologically presenting as a mixed radiolucent radiopaque lesion showing nonspecific cystic degeneration.