Open AccessAn immunohistochemical study of basement membrane heparan sulfate proteoglycan (perlecan) in oral epithelial dysplasia and squamous cell carcinoma
Author(s) -
Mithilesh Mishra,
Vidyadevi Chandavarkar,
Veena V. Naik,
Alka D Kale
Publication year - 2013
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.110704
Subject(s) - perlecan , basement membrane , epithelial dysplasia , pathology , heparan sulfate , epithelium , immunohistochemistry , dysplasia , biology , metastasis , cancer , proteoglycan , cell , cancer research , extracellular matrix , medicine , microbiology and biotechnology , genetics
Basement membrane heparan sulfate proteoglycan (perlecan) has been demonstrated in precancer lesions and carcinomas of oral cavity. It helps in malignant transformation of epithelial cells. The aim of our study was to understand the immuno-localization of perlecan in oral dysplastic epithelium and oral carcinomas.