Open AccessConcomitant falciparum malaria and Hyperreactive Malarial Splenomegaly in an adolescent boy from eastern India: A tale of rare coincidences
Author(s) -
Saurabh Pandey,
Prantiki Halder,
Arnab Patra,
Mausam Mondal,
Subir Ghosh,
Dipankar Pal,
Soumen Nath Halder,
Dolon Champa Modak,
Subhashish Kamal Guha
Publication year - 2020
Publication title -
journal of vector borne diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.581
H-Index - 41
ISSN - 0972-9062
DOI - 10.4103/0972-9062.311782
Subject(s) - malaria , concomitant , jaundice , pancytopenia , chloroquine , context (archaeology) , medicine , immunology , plasmodium falciparum , pediatrics , biology , bone marrow , paleontology
Hyperreactive malarial splenomegaly (HMS) is one of the important causes of massive splenomegaly in malaria endemic zones. It is thought to represent a dysfunctional immune response to recurrent malarial infection. It is usually reported due to physical symptoms of splenomegaly and hypersplenism and fever is classically absent. Concomitant malaria with HMS is a very rare finding in the Indian context. Here, we report a case of symptomatic falciparum malaria presented with fever, jaundice, massive splenomegaly and pancytopenia. Persistent massive splenomegaly led us to investigate thoroughly and finally diagnosed it as HMS with concomitant falciparum malaria. He received standard antimalarial treatment and 12 months of weekly chloroquine and completely recovered without any relapse or complications.