Open AccessC-reactive protein as a prognostic marker of Plasmodiumfalciparum malaria severity
Author(s) -
Nitin Bhardwaj,
Zohaib Ahmed,
Supriya Sharma,
Akshatha Nayak,
Anupkumar R. Anvikar,
Veena Pande
Publication year - 2019
Publication title -
journal of vector borne diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.581
H-Index - 41
ISSN - 0972-9062
DOI - 10.4103/0972-9062.263727
Subject(s) - malaria , medicine , c reactive protein , gastroenterology , acute phase protein , receiver operating characteristic , diagnosis of malaria , case control study , immunology , plasmodium falciparum , inflammation
Plasmodiumfalciparum malaria causes wide variety of clinical symptoms ranging from a mild febrile illness to life-threatening complications. For prevention of the severity and early diagnosis, evaluation of potential biomarkers is much needed. C-reactive protein (CRP) is an acute phase protein and well-recognized marker of inflammation in the body. It is synthesized by liver in response to pro-inflammatory responses and has correlation with complications associated with malaria. The study was aimed to assess, if it could serve as a predictive marker for malaria disease severity.