Open AccessEffectiveness of early start of direct hemoperfusion with polymyxin B-immobilized fiber columns judging from stabilization in circulatory dynamics in surgical treatment patients
Author(s) -
Yuichiro Sakamoto,
Kunihiro Mashiko,
Toru Obata,
Hisashi Matsumoto,
Yoshiaki Hara,
Noriyoshi Kutsukata,
Hiroyuki Yokota
Publication year - 2010
Publication title -
indian journal of critical care medicine/indian journal of critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 30
eISSN - 1998-359X
pISSN - 0972-5229
DOI - 10.4103/0972-5229.63032
Subject(s) - hemoperfusion , medicine , septic shock , sofa score , apache ii , sepsis , mortality rate , polymyxin b , survival rate , shock (circulatory) , surgery , anesthesia , intensive care unit , antibiotics , hemodialysis , microbiology and biotechnology , biology
Septic shock remains a major cause of multiple organ failure and is associated with a high mortality rate. In 1994, direct hemoperfusion using a polymyxin B-immobilized fiber column (PMX; Toray Industries Inc., Tokyo Japan) was developed in Japan and has since been used for the treatment of septic shock arising from endotoxemia.