Open AccessDynamic changes of plasma neutrophil gelatinase-associated lipocalin predicted mortality in critically ill patients with systemic inflammatory response syndrome
Author(s) -
Azrina Ralib,
Suhaila Nanyan,
Mohd Basri Mat Nor
Publication year - 2017
Publication title -
indian journal of critical care medicine/indian journal of critical care medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 30
eISSN - 1998-359X
pISSN - 0972-5229
DOI - 10.4103/0972-5229.198322
Subject(s) - medicine , systemic inflammatory response syndrome , lipocalin , intensive care unit , odds ratio , prospective cohort study , systemic inflammation , neutrophil gelatinase associated lipocalin , gastroenterology , sepsis , inflammation
About 50% of patients admitted to the Intensive Care Unit have systemic inflammatory response syndrome (SIRS), and about 10%-20% of them died. Early risk stratification is important to reduce mortality. Plasma neutrophil gelatinase-associated lipocalin (NGAL) is increased by inflammation and infection. Its ability to predict mortality in SIRS patients is of interest. We evaluated the ability of serial measurement of NGAL for the prediction of mortality in critically ill patients with SIRS.