Open AccessSomatostatin receptor spect/ct using 99mTc labeled hynic-toc aids in diagnosis of primary optic nerve sheath meningioma
Author(s) -
Piyush Chandra,
Nilendu Purandare,
Sneha Shah,
Archi Agrawal,
Venkatesh Rangarajan
Publication year - 2017
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.198487
Subject(s) - medicine , somatostatin receptor , meningioma , magnetic resonance imaging , differential diagnosis , somatostatin , optic nerve , nuclear medicine , pathology , radiology , anatomy
Primary optic nerve sheath meningiomas (ONSM) are rare, benign and slow growing tumor involving the intra-orbital/intra-canalicular segment of the optic nerve. Untreated, they can potentially lead to visual deterioration. Magnetic resonance (MR) is the gold standard imaging modality for diagnosing the entity. Often, a clinical dilemma exists to narrow the differential diagnosis of an enhancing intra-orbital mass on MR. Molecular imaging provides a high degree of precision in diagnosing meningioma in view of relatively high levels of somatostatin receptor expression by these tumors. The following case demonstrates the potential clinical utility of somatostatin receptor SPECT using 99m Tc- labeled HYNIC-TOC in clinical diagnosis of ONSM.