Open Access18F-Fluorodeoxyglucose positron emission tomography/computed tomography scan in an unusual case of lymphoma with secondary involvement of uterine cervix presenting as a pathological fracture
Author(s) -
Arun Sasikumar,
Ajith Joy,
M.R.A. Pillai,
Boben Thomas
Publication year - 2017
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.198483
Subject(s) - medicine , radiology , positron emission tomography , lymphoma , biopsy , pathological , fluorodeoxyglucose , cervix , nuclear medicine , pathology , cancer
A 48-year-old female presented with a pathological fracture of the right femur. 99m Tc methylene diphosphonate bone scan revealed multiple areas of increased osteoblastic activity consistent with metastatic disease. Serum electrophoresis revealed monoclonal gammopathy. 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) scan revealed metabolically active lesions in bulky uterine cervix and osteolytic skeletal lesions. Unusual pattern of FDG uptake in uterine cervix and osteolytic skeletal lesions warranted a biopsy of the uterine cervix which revealed diffuse large B-cell lymphoma. 18 F-FDG PET/CT scan helped in guiding the site of biopsy to reach a final diagnosis in this unusual case of lymphoma with a secondary involvement of uterine cervix presenting as a pathological fracture.