Open AccessRole of 99m Tc-MDP bone scan in the diagnosis of Erdheim-Chester disease
Author(s) -
Anirban Mukherjee,
Nishikant Damle,
Chandrasekhar Bal,
Aashima Arora,
Abhinav Singhal,
Madhavi Tripathi,
Karan Peepre
Publication year - 2014
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.136575
Subject(s) - medicine , erdheim–chester disease , disease , nuclear medicine , radiology , pathology , histiocytosis
Erdheim-Chester disease (ECD) is a rare systemic non-Langerhans cell histiocytosis. It is a progressive disease of unknown etiology. The (99m)technetium-methylene diphosphonate ((99m)Tc-MDP) bone scan is useful in finding the sites of involvement in the skeleton and is helpful in excluding other causes of bony pain. Also a scintigraphic pattern consistent with ECD should alert the physician to evaluate the patient for visceral sites of involvement using fludeoxyglucose positron emission tomography/computed tomography (FDG PET/CT), as this is known to be fatal at times.