Open Access18F-fluorodeoxyglucose positron emission tomography/computed tomography in a case of malignant peripheral nerve sheath tumor: An unusual presentation
Author(s) -
Maria D’Souza,
Abhinav Jaimini,
Tapan Kumar Dhali,
Paschal D’Souza,
Sanjiv Saw,
Rajnish Sharma,
Anupam Mondal
Publication year - 2013
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.119551
Subject(s) - medicine , neurofibromatosis , malignant peripheral nerve sheath tumor , fluorodeoxyglucose , positron emission tomography , peripheral , soft tissue , radiology , presentation (obstetrics) , pathology , nuclear medicine
Malignant peripheral nerve sheath tumors (MPNSTs) are rare tumors, with an estimated incidence of 0.1/100,000/year. They are regarded as a rare variety of soft-tissue sarcomas that derive from peripheral nerves or from cells associated with the nerve sheath. Until 50% of observed MPNSTs occur in patients with neurofibromatosis 1 (NF1). The typical presenting signs and symptoms of a PNST are a palpable mass involving a peripheral nerve, loss of nerve function and/or pain. Recently, positron emission tomography (PET) has been used to detect 18F-fluorodeoxyglucose uptake in these tumors. Most of the PET studies have been reported in patients with NF1. We report a case of sporadic MPNST masquerading as infectious dermatoses, with an unusual PET/computed tomography presentation.