Open AccessHemimegalencephaly: A rare cause of hemihypoperfusion on 99m technetium-ethyl cysteinate dimer brain perfusion single-photon emission computed tomography
Author(s) -
Nishikant Damle,
Abhinav Singhal,
Anirban Mukherjee,
Manoranjan Sahoo,
Madhavi Tripathi,
Chandrasekhar Bal
Publication year - 2013
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.118257
Subject(s) - hemimegalencephaly , medicine , technetium 99m , single photon emission computed tomography , perfusion , emission computed tomography , radiology , nuclear medicine , perfusion scanning , hemispherectomy , epilepsy , magnetic resonance imaging , cortical dysplasia , scintigraphy , psychiatry
Hemimegalencephaly is a rare congenital neuronal migration disorder that can presents with the equally rare finding of hemihypoperfusion on brain perfusion single-photon emission computed tomography (SPECT). It is an extremely rare cause of intractable epilepsy. Technetium-99m ethyl cysteinate dimer (ECD) brain perfusion SPECT is useful in excluding other foci of hypoperfusion in the contralateral since hemispherectomy has been suggested to be the treatment of choice. Furthermore, hemimegalencephaly may present with hyper as well as hypoperfusion on ECD SPECT. We present the case of an 11-year-old male child with intractable seizures who showed hemihypoperfusion in the hemimegalecephalic hemisphere.