Open AccessLytic and sclerotic (mixed) vertebral metastasis in ganglioneuroblastoma
Author(s) -
Sridhar Sivasubbu,
Sanjay Kumar Bhadada,
Anil Bhansali,
Anish Bhattacharya
Publication year - 2012
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.110721
Subject(s) - ganglioneuroblastoma , medicine , lytic cycle , neuroblastoma , metastasis , presentation (obstetrics) , radiology , bone metastasis , computed tomography , positron emission tomography , positron emission tomography computed tomography , pathology , cancer , ganglioneuroma , immunology , virus , genetics , biology , cell culture
The clinical presentation of ganglioneuroblastoma is highly variable and it is not uncommon to see metastasis at presentation. Bone is the second most common site of metastasis in neuroblastoma. Neuroblastoma cells usually activate osteoclasts and form osteolytic lesions. Here, we describe a patient who presented with back pain. On evaluation, X-ray and positron emission tomography-computed tomography showed mixed lytic and sclerotic vertebral metastasis, and subsequently diagnosed as ganglioneuroblastoma.