Open AccessIodine-131 meta-iodobezylguanidine single photon emission computed tomography/computerized tomography in diagnosis of neuro-endocrine tumors
Author(s) -
Chidambaram Natrajan Balasubramanian Harisankar,
Bhagwant Rai Mittal,
Anish Bhattacharya,
Raghava Kashyap,
Anil Bhansali
Publication year - 2012
Publication title -
indian journal of nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.261
H-Index - 13
eISSN - 0972-3919
pISSN - 0974-0244
DOI - 10.4103/0972-3919.108877
Subject(s) - medicine , tomography , single photon emission computed tomography , emission computed tomography , iodine , endocrine system , radiology , nuclear medicine , iodine 123 , positron emission tomography , hormone , materials science , metallurgy
Metaiodobenzyl guanidine (MIBG) is a derivative of guanethidine and acts as an analogue of nor-epinephrine and is widely used in the imaging of tumors of neuro-endocrine origin. Iodine-123 MIBG has ideal imaging characteristics but is expensive with limited availability. Iodine-131 MIBG is widely used in India and is cheap. Hybrid single photon emission computed tomography (SPECT)/computerized tomography (CT) allows for anatomico-functional imaging and is being tried in MIBG studies. However, the experience with I-131 MIBG is limited. We present a pictorial assay of I-131 MIBG SPECT/CT findings in various MIBG avid tumors.