Open AccessKleine-Levine syndrome in an adolescent female and response to modafinil
Author(s) -
Ashish Aggarwal,
Amit Garg,
RC Jiloha
Publication year - 2011
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.78052
Subject(s) - modafinil , narcolepsy , hypersexuality , medicine , stimulant , psychiatry , mood , bipolar disorder , pediatrics , clinical psychology , sexual behavior
Kleine-Levine Syndrome (KLS) is a disorder characterized by a triad of periodic hypersomnia, hyperphagia, and hypersexuality. KLS, although more common in young males, it has also been seen in females. Treatment options available for its management include mood stabilisers like lithium, stimulants like amphetamines, antidepressants and other options including electroconvulsive therapy. Modafinil is one of the new stimulant medications approved for narcolepsy. Herein, we report a young female with KLS and showing favorable response to modafinil. More data is required to establish the effectiveness of modafinil in this syndrome.