Open AccessOpsoclonus-myoclonus syndrome caused by varicella-zoster virus
Author(s) -
Dilip Kumar Singh,
Mumun Sinha,
Rajesh Kumar,
Rakesh Shukla,
Ahuja Rc
Publication year - 2010
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.70876
Subject(s) - medicine , myoclonus , clonazepam , opsoclonus , asymptomatic , cerebrospinal fluid , neuroblastoma , varicella zoster virus , virus , antibody , pediatrics , dermatology , virology , immunology , pathology , anesthesia , biology , genetics , cell culture
Opsoclonus-myoclonus syndrome (OMS) is a rare condition that has been reported from all parts of the world. It is well recognized as a paraneoplastic syndrome in children with neuroblastoma and in adults with small-cell carcinoma of lung and some other cancers. It may also occur in association with various central nervous system infections. We report a case of OMS in a patient with varicella zoster virus infection. IgM antibody for varicella-zoster virus was detected in the serum and the cerebrospinal fluid. The patient improved after treatment with clonazepam and was asymptomatic at 1-month follow-up.