Opsoclonus-myoclonus syndrome caused by varicella-zoster virus | Zendy

Rakesh Shukla | Zendy; Dilip Singh | Zendy; Manish Kumar Sinha | Zendy; Rajesh Kumar | Zendy; Ahuja Rc | Zendy

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Opsoclonus-myoclonus syndrome caused by varicella-zoster virus

Author(s) -

Rakesh Shukla,

Dilip Singh,

Manish Kumar Sinha,

Rajesh Kumar,

Ahuja Rc

Publication year - 2010

Publication title -

annals of indian academy of neurology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 31

eISSN - 1998-3549

pISSN - 0972-2327

DOI - 10.4103/0972-2327.70876

Subject(s) - medicine , myoclonus , clonazepam , opsoclonus , asymptomatic , cerebrospinal fluid , neuroblastoma , varicella zoster virus , virus , antibody , pediatrics , dermatology , virology , immunology , pathology , anesthesia , biology , genetics , cell culture

Opsoclonus-myoclonus syndrome (OMS) is a rare condition that has been reported from all parts of the world. It is well recognized as a paraneoplastic syndrome in children with neuroblastoma and in adults with small-cell carcinoma of lung and some other cancers. It may also occur in association with various central nervous system infections. We report a case of OMS in a patient with varicella zoster virus infection. IgM antibody for varicella-zoster virus was detected in the serum and the cerebrospinal fluid. The patient improved after treatment with clonazepam and was asymptomatic at 1-month follow-up.

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