Open AccessAssessment of cerebrovascular reactivity during major depression and after remission of disease
Author(s) -
Alireza Vakilian,
Farhad Iranmanesh
Publication year - 2010
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.61278
Subject(s) - medicine , transcranial doppler , depression (economics) , cerebral blood flow , cardiology , middle cerebral artery , cerebral autoregulation , stroke (engine) , anesthesia , autoregulation , blood pressure , ischemia , mechanical engineering , economics , engineering , macroeconomics
There are a growing number of studies suggesting that depression may increase the risk of stroke. Impaired autoregulation of vascular tone may contribute to a higher risk of developing cerebrovascular diseases. Cerebrovascular reactivity (CVR) reflects the compensatory dilatory capacity of cerebral arterioles to a dilatory stimulus and is an important mechanism that ensures constant cerebral blood flow. There is a hypothesis that CVR is reduced in major depression, which would explain the association between depression and stroke.