
Perineural spread of rhino-orbitocerebral mucormycosis caused by Apophysomyces elegans
Author(s) -
Kirti Parsi,
Raghavendra K Itgampalli,
R Vittal,
Atul Kumar
Publication year - 2013
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.116921
Subject(s) - mucormycosis , medicine , trigeminal nerve , perineural invasion , dermatology , pathology , anatomy , cancer
Rhino-orbitocerebral mucormycosis (ROCM) is a fungal infection commonly affecting individuals with diabetes and those in immunocompromised states. However, infections caused by Apophysomyces elegans can involve immunocompetent individuals. The invasion pattern of cerebral mucormycosis is somewhat predictable and may occur by direct invasion or hematogenous spread. Perineural spread of the disease is unusual. Here, we report the first case of perineural extension of ROCM caused by A. elegans along the trigeminal nerve in a 25-year-old immunocompetent, nondiabetic individual.