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Recurrent craniospinal subarachnoid hemorrhage in cerebral amyloid angiopathy
Author(s) -
M Alexander,
Anil Kumar Patil,
Vivek Mathew,
Ajith Sivadasan,
Geeta Chacko,
Sunithi Mani
Publication year - 2013
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.107712
Subject(s) - superficial siderosis , medicine , cerebral amyloid angiopathy , subarachnoid hemorrhage , siderosis , intraventricular hemorrhage , magnetic resonance imaging , intracerebral hemorrhage , hemosiderosis , radiology , pathology , surgery , disease , dementia , pregnancy , biology , genetics , gestational age
Cerebral amyloid angiopathy (CAA) usually manifests as cerebral hemorrhage, especially as nontraumatic hemorrhages in normotensive elderly patients. Other manifestations are subarachnoid (SAH), subdural, intraventricular hemorrhage (IVH) and superficial hemosiderosis. A 52-year-old hypertensive woman presented with recurrent neurological deficits over a period of 2 years. Her serial brain magnetic resonance imaging and computed tomography scans showed recurrent SAH hemorrhage, and also intracerebral, IVH and spinal hemorrhage, with superficial siderosis. Cerebral angiograms were normal. Right frontal lobe biopsy showed features of CAA. CAA can present with unexplained recurrent SAH hemorrhage, and may be the initial and prominent finding in the course of disease in addition to superficial cortical siderosis and intracerebal and spinal hemorrhages.

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