Open AccessQuantitative thermal sensory testing and sympathetic skin response in primary Restless legs syndrome - A prospective study on 57 Indian patients
Author(s) -
Garima Shukla,
Vinay Goyal,
Achal K. Srivastava,
Madhuri Behari
Publication year - 2012
Publication title -
annals of indian academy of neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 31
eISSN - 1998-3549
pISSN - 0972-2327
DOI - 10.4103/0972-2327.104332
Subject(s) - medicine , peripheral , quantitative sensory testing , sensory system , peripheral nervous system , sympathetic nervous system , peripheral neuropathy , nervous system , dopaminergic , restless legs syndrome , dopaminergic pathways , neuroscience , central nervous system , dopamine , neurology , endocrinology , blood pressure , psychiatry , biology , diabetes mellitus
Patients with restless leg syndrome present with sensory symptoms similar to peripheral neuropathy. While there is evidence of abnormalities of dopaminergic pathways, the peripheral nervous system has been studied infrequently. We studied conventional nerve conduction studies, quantitative thermal sensory testing and sympathetic skin response in 57 patients with primary restless leg syndrome. Almost two third patients demonstrated abnormalities in the detailed testing of the peripheral nervous system. Sbtle abnormalities of the peripheral nervous system may be more common than previously believed.