Open AccessAnaplastic lymphoma kinase positive variant of anaplastic large cell lymphoma: A rare entity
Author(s) -
Venkata Satya Ramesh Thummala,
Sreenidhi Banda,
Vinay Kumar Reddy Kundoor,
Kotya Naik Maloth
Publication year - 2014
Publication title -
journal of indian academy of oral medicine and radiology
Language(s) - English
Resource type - Journals
eISSN - 0975-1572
pISSN - 0972-1363
DOI - 10.4103/0972-1363.155640
Subject(s) - medicine , anaplastic large cell lymphoma , cd30 , lymphoma , anaplastic lymphoma kinase , pathology , immunohistochemistry , large cell , neoplasm , t cell lymphoma , cancer , adenocarcinoma , malignant pleural effusion , lung cancer
Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin′s lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticular organs, intraoral swellings, and characteristic hallmark cells (eccentric, kidney-shaped, or horseshoe-shaped nuclei) and cluster of differentiation 30 (CD30) positivity. Thorough clinical, biochemical, immunohistochemical, histopathological, and radiological evaluation aids in accurate diagnosis and management of the disease. Here, we report a case of anaplastic lymphoma kinase positive variant of ALCL in a 13-year-old boy