Open AccessEfficacy of a chairside diagnostic test kit for estimation of C-reactive protein levels in periodontal disease
Author(s) -
Girish Nagarale,
Savita Ravindra,
Srinath Thakur,
Swati Setty
Publication year - 2010
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.76919
Subject(s) - medicine , c reactive protein , periodontitis , gingivitis , gastroenterology , chronic periodontitis , dentistry , latex fixation test , immunology , inflammation , antibody
C-reactive protein [CRP] levels increase to hundreds of mg/mL within hours following infection. Studies have shown that serum CRP levels were elevated in periodontal disease. However, in all the previous studies, CRP levels were measured by using high-sensitivity CRP assay kits with minimal detection limits of 0.1 to 3 mg/L, which was much below the normal value of 10 mg/L. These high-sensitivity CRP assays need a proper laboratory setup, and these methods cannot be used as a routine chair-side test in the dental office.