Open AccessEvaluation of an aminobisphosphonate (alendronate) in the management of periodontal osseous defects
Author(s) -
H R Veena,
Deepak Prasad
Publication year - 2010
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.65438
Subject(s) - medicine , periodontitis , dentistry , debridement (dental) , placebo , dental alveolus , chronic periodontitis , radiography , bisphosphonate , surgery , osteoporosis , pathology , alternative medicine
Alendronate, an aminobisphosphonate, is capable of inhibiting periodontitis associated osteoclastic activity and hence is effective in protecting the alveolar bone in periodontitis. In the present study, we explored the efficacy of local delivery of alendronate on the alveolar bone following mucoperiosteal flap surgery. This is the first study to use polymer impregnated gel based delivery of alendronate.