Open AccessEvaluation of plasma C-reactive protein levels in pregnant women with and without periodontal disease: A comparative study
Author(s) -
Ashok K. Sharma,
Amitha Ramesh,
Biju Thomas
Publication year - 2009
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.60227
Subject(s) - medicine , c reactive protein , pregnancy , gestation , preeclampsia , periodontitis , obstetrics , birth weight , incidence (geometry) , low birth weight , gestational age , premature birth , gastroenterology , inflammation , genetics , physics , optics , biology
Circulating C-reactive protein (CRP) levels are a marker of systemic inflammation and are associated with periodontal disease, a chronic bacterial infection associated with elevation of proinflammatory cytokines and prostaglandins. CRP has been associated with adverse pregnancy outcomes, including preterm delivery, preeclampsia, and intrauterine growth restriction. Furthermore, periodontal disease has been associated with increased risk of preterm low birth weight, low birth weight, and preterm birth. The present study was conducted to assess plasma CRP levels in pregnant women with and without periodontal disease; to evaluate the effect of periodontal therapy on the incidence of preterm delivery; and to compare the incidence of preterm delivery in pregnant women with and without periodontal disease.