Open AccessTumor necrosis factor-α, interleukin-4 and -6 in the serum of health, chronic periodontitis, and type 2 diabetes mellitus
Author(s) -
Anirudh B. Acharya,
Srinath Thakur,
M.V. Muddapur,
Raghavendra Kulkarni
Publication year - 2016
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.201694
Subject(s) - medicine , glycated hemoglobin , tumor necrosis factor alpha , periodontitis , diabetes mellitus , type 2 diabetes mellitus , immunology , chronic periodontitis , glycemic , cytokine , interleukin , inflammation , type 2 diabetes , endocrinology
Cytokines are significant in the development and progression of chronic periodontitis (ChP) and type 2 diabetes mellitus (DT2). Insufficient information is available regarding the pro- versus anti-inflammatory cytokines in ChP's influence on systemic levels of cytokines on DT2. This study investigated the levels of tumor necrosis factor-α (TNF-α), interleukin (IL)-4 and IL-6 in the serum of patients with ChP, DT2, and with both ChP and DT2, as compared to health.