Relationship between interleukin 1α levels in the gingival crevicular fluid in health and in inflammatory periodontal disease and periodontal inflamed surface area: A correlative study | Zendy

Kalaichelvi Govindarajan | Zendy; Santhanakrishnan Muthukumar | Zendy; Suresh Rangarao | Zendy

Open Access

Relationship between interleukin 1α levels in the gingival crevicular fluid in health and in inflammatory periodontal disease and periodontal inflamed surface area: A correlative study

Author(s) -

Kalaichelvi Govindarajan,

Santhanakrishnan Muthukumar,

Suresh Rangarao

Publication year - 2015

Publication title -

journal of indian society of periodontology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.309

H-Index - 28

eISSN - 0975-1580

pISSN - 0972-124X

DOI - 10.4103/0972-124x.162197

Subject(s) - medicine , statistical significance , periodontitis , clinical attachment loss , pathological , periodontal disease , gingival and periodontal pocket , inflammation , dentistry , clinical significance , positive correlation , gastroenterology

Periodontitis has been suggested as a source of inflammation for pathological changes in distant sites. Interleukin-1 alpha (IL-1α) has shown to have specific roles in inflammation, immunity, tissue breakdown, and tissue homeostasis. This study assessed the correlation of periodontal inflamed surface area (PISA) index with the gingival crevicular fluid (GCF) levels of IL-1α, which would be helpful in evaluating the validity of PISA index in terms of reflection of the disease.

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