Open AccessRelationship between interleukin 1α levels in the gingival crevicular fluid in health and in inflammatory periodontal disease and periodontal inflamed surface area: A correlative study
Author(s) -
Kalaichelvi Govindarajan,
Subramanian Muthukumar,
Suresh Rangarao
Publication year - 2015
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.162197
Subject(s) - medicine , statistical significance , periodontitis , clinical attachment loss , pathological , periodontal disease , gingival and periodontal pocket , inflammation , dentistry , clinical significance , positive correlation , gastroenterology
Periodontitis has been suggested as a source of inflammation for pathological changes in distant sites. Interleukin-1 alpha (IL-1α) has shown to have specific roles in inflammation, immunity, tissue breakdown, and tissue homeostasis. This study assessed the correlation of periodontal inflamed surface area (PISA) index with the gingival crevicular fluid (GCF) levels of IL-1α, which would be helpful in evaluating the validity of PISA index in terms of reflection of the disease.