Open AccessRecombinant human bone morphogenetic protein type 2 in the reconstruction of atrophic maxilla: Case report with long-term follow-up
Author(s) -
André Luís Zétola,
Thalyta Verbicaro,
Sahara Littieri,
Rafaela Larson,
Allan Fernando Giovanini,
Tatiana Miranda Deliberador
Publication year - 2014
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.147437
Subject(s) - medicine , bone grafting , bone morphogenetic protein , maxilla , dentistry , osseointegration , human bone , recombinant dna , bone morphogenetic protein 2 , surgery , implant , biochemistry , chemistry , in vitro , gene
Autologous bone is reported by scientific literature as the gold standard for the replacement of the bone loss in maxillary atrophic area. Notwithstanding, this grafting type shows several disadvantages as: The procedure morbidity, limited size of the graft and longer recovering time. Recombinant human bone morphogenetic protein type 2 (rhBMP-2) has been used as bone substitute for the reconstruction of large bone defects. The aim of this case was to report a clinical case exhibiting the reconstruction of the atrophic maxilla through using rhBMP-2 as grafting material associated with absorbable collagen sponge (ACS). At 8 months of following-up, osseointegrated implants were placed. After 2 years and 5 months of following-up, it could be observed an appropriate aesthetical and functional rehabilitation.