Open AccessToll-like receptor 9 gene polymorphism in chronic and aggressive periodontitis patients
Author(s) -
Nipun Ashok,
Shivaraj Warad,
Nagaraj B Kalburgi,
Shivaprasad Bilichodmath,
Prabath Singh Valiyaparambil Prabhakaran,
Bassel Tarakji
Publication year - 2014
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.147407
Subject(s) - chronic periodontitis , aggressive periodontitis , medicine , genotype , periodontitis , immunology , allele , population , etiology , allele frequency , genetic predisposition , gene , genetics , disease , biology , environmental health
Periodontitis is a multifactorial disease, with microbial dental plaque as the primary etiological factor. However, the manifestation and progression of periodontitis is influenced by a wide variety of other determinants and factors such as social and behavioral factors, systemic factors, microbial composition of dental plaque, genetic, and many other emerging risk factors. The aim of this study was to analyze genetic polymorphisms in the toll-like receptor 9 (TLR9) gene at - 1237C/T and its association with chronic and generalized aggressive periodontitis (GAgP) in an Indian population.