Open AccessEstimation of tissue inhibitor of matrix metalloproteinase-1 levels in gingival crevicular fluid in periodontal health, disease and after treatment
Author(s) -
Nagireddy Ravindra Reddy,
Deepa Anumala,
Dandu Subramanyam Madhu Babu,
Nelapati Sarath Chandra,
Chowdawaram Venkat Subba Reddy,
Avula Kishore Kumar
Publication year - 2014
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.134565
Subject(s) - medicine , periodontal disease , scaling and root planing , chronic periodontitis , gastroenterology , dentistry , periodontitis , biomarker , matrix metalloproteinase , clinical attachment loss , disease , biochemistry , chemistry
Initial research has shown a negative correlation between the severity of periodontal disease and tissue inhibitor of matrix metalloproteinases (TIMPs) concentrations in gingival crevicular fluid (GCF). However, there are no enough reports to correlate the TIMP-1 concentrations in GCF in periodontal health, disease and after treatment. Hence, the present study aim is to estimate the levels of TIMP-1 in GCF in periodontal health, disease and to evaluate the effect of periodontal therapy on TIMP-1 concentrations in GCF.