Open AccessAn insight into the possibilities of fibroblast growth factor in periodontal regeneration
Author(s) -
Sameera G Nath,
Ranjith Raveendran
Publication year - 2014
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.134560
Subject(s) - regeneration (biology) , periodontal fiber , medicine , enamel matrix derivative , periodontitis , fibroblast , dentistry , basic fibroblast growth factor , fibroblast growth factor , tissue engineering , biofilm , growth factor , microbiology and biotechnology , biology , biomedical engineering , cell culture , genetics , receptor , bacteria
Periodontitis is caused by bacterial biofilms and is modulated by a variety of risk factors. The periodontal ligament comprises heterogeneous cell populations which are lost in the disease process. A variety of regenerative therapies, such as bone grafts, guided tissue regeneration treatment, application of enamel matrix derivative, have been introduced, with some success in periodontal tissue regeneration. Topical application of recombinant cytokines is now one of the most effective methods to stimulate stem cells. Researchers are now exploring the potential applications and uses of fibroblast growth factor in periodontal regeneration.