Open AccessComparative evaluation of the efficacy of the cyclooxygenase pathway inhibitor and nitric oxide synthase inhibitor in the reduction of alveolar bone loss in ligature induced periodontitis in rats: An experimental study
Author(s) -
Rekha Jagadish,
Dhoom Singh Mehta
Publication year - 2014
Publication title -
journal of indian society of periodontology (print)/journal of indian society of periodontology (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.309
H-Index - 28
eISSN - 0975-1580
pISSN - 0972-124X
DOI - 10.4103/0972-124x.128216
Subject(s) - dental alveolus , medicine , periodontitis , nitric oxide synthase , bone resorption , diclofenac sodium , nitric oxide , cyclooxygenase , pharmacology , pathology , dentistry , enzyme , chemistry , biochemistry
Alveolar bone loss is the most striking feature of periodontal disease. The aim of this study was to investigate the effect of a cyclooxygenase (COX) pathway inhibitor and nitric oxide synthase (NOS) inhibitor in the reduction of alveolar bone loss in an experimental periodontal disease (EPD) model.