Open AccessInduced mild hypothermia in post-cardiopulmonary bypass vasoplegia syndrome
Author(s) -
Mukesh Tripathi,
Prabhat Kumar Singh,
Narendra Kumar,
K. C. Pant
Publication year - 2009
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/0971-9784.45013
Subject(s) - medicine , cardiopulmonary bypass , vascular resistance , hypothermia , anesthesia , cardiology , oxygenation , ventricle , inotrope , pulmonary hypertension , epinephrine , cardiac output , blood pressure
The state of vasoplegia in immediate post-cardiopulmonary bypass period is characterized by severe hypotension, supranormal cardiac output, low systemic vascular resistance (SVR), and resistance to vasoconstrictors. We could successfully use induced mild hypothermia to increase SVR, and could avoid very high doses of nor-epinephrine (>0.3 mcg/kg/min) in the background of severe pulmonary hypertension (systolic pulmonary pressure> 90 mmHg). Its effects such as decreased oxygen demand, positive inotropy and better right ventricle performance probably helped to improve oxygenation in presence of pulmonary oedema.