Open AccessPhenylephrine postconditioning increases myocardial injury: Are alpha-1 sympathomimetic agonist cardioprotective?
Author(s) -
Iordanis Mourouzis,
Theodosios Saranteas,
Heidi Ligeret,
Christophe Portal,
P. Périménis,
Constantinos Pantos
Publication year - 2014
Publication title -
annals of cardiac anaesthesia/annals of cardiac anaesthesia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.42
H-Index - 27
eISSN - 0974-5181
pISSN - 0971-9784
DOI - 10.4103/0971-9784.135850
Subject(s) - medicine , phenylephrine , lactate dehydrogenase , p38 mitogen activated protein kinases , protein kinase b , endocrinology , protein kinase a , agonist , cardioprotection , reperfusion injury , kinase , mapk/erk pathway , ischemia , apoptosis , pharmacology , receptor , chemistry , enzyme , biochemistry , blood pressure
We studied effects of phenylephrine (PHE) on postischemic functional recovery and myocardial injury in an ischemia-reperfusion (I-R) experimental model.