Open AccessThe role of nitric oxide in portal hypertension caused by extrahepatic portal vein obstruction
Author(s) -
Pankaj Goel,
Kamna Srivastava,
Nibhriti Das,
Veereshwar Bhatnagar
Publication year - 2010
Publication title -
journal of indian association of pediatric surgeons
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1998-3891
pISSN - 0971-9261
DOI - 10.4103/0971-9261.72433
Subject(s) - medicine , portal hypertension , shunt (medical) , portal venous pressure , surgery , splenectomy , nitric oxide , portography , gastroenterology , cardiology , cirrhosis , spleen
Nitric oxide (NO) in peripheral venous blood has been shown to be elevated in experimental portal hypertension. This study aims to determine the serum NO levels in patients with extrahepatic portal venous hypertension (EHPVO) pre- and postoperatively and to analyze whether these can serve as a reliable and early indicator of shunt blockage or malfunction.