Open AccessCoexisting urogenital anomaly and duodenal atresia in two atypical Holt-Oram syndrome
Author(s) -
Tuncer Ahmet Ali,
Afra Karavelioğlu,
Didem Baskın Embleton,
Muhsin Elmas
Publication year - 2016
Publication title -
journal of indian association of pediatric surgeons
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1998-3891
pISSN - 0971-9261
DOI - 10.4103/0971-9261.186552
Subject(s) - medicine , hypospadias , renal agenesis , duodenal atresia , genitourinary system , horseshoe kidney , atresia , dysplasia , agenesis , renal dysplasia , anatomy , hydronephrosis , kidney , urinary system
Holt-Oram syndrome (HOS) is a rare autosomal dominant disorder, characterized by upper limb dysplasia and congenital cardiac defect. We report two cases with HOS, first associated with renal agenesis, coronal hypospadias, urethral duplication and second associated with duodenal atresia and horseshoe kidney that have not been reported in English literature.