Open AccessNon-rhabdomyosarcoma soft-tissue sarcomas in children: Contemporary appraisal and experience from a single centre
Author(s) -
Sajid Qureshi,
Monica Bhagat
Publication year - 2015
Publication title -
journal of indian association of pediatric surgeons
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.306
H-Index - 17
eISSN - 1998-3891
pISSN - 0971-9261
DOI - 10.4103/0971-9261.154664
Subject(s) - medicine , soft tissue , rhabdomyosarcoma , soft tissue sarcoma , radiation therapy , chemotherapy , sarcoma , disease , oncology , pathology , surgery
Nonrhabdmyosarcoma soft tissue sarcomas (NRSTS) include a cluster of different types of soft tissue sarcomas clubbed together due to the rarity of individual subtypes. The diagnostic accuracy is lately reinforced due to the availability of immunohistochemical and molecular markers. Surgery is the central modality of treatment since many of them are insensitive to chemotherapy. With the availability of rational risk stratification system, efforts are in progress to evaluate the role of neoadjuvant chemotherapy and radiotherapy to improve outcomes especially for the locally advanced disease. The survival remains dismal for metastatic disease. This review highlights the current status of NRSTS and also describes the experience from a single centre in treatment of NRSTS.