Open AccessClinical, hematologic and molecular variability of sickle cell-β thalassemia in western India
Author(s) -
Malay B. Mukherjee,
Anita Nadkarni,
Ajit Gorakshakar,
Kanjaksha Ghosh,
Dipika Mohanty,
Roshan Colah
Publication year - 2010
Publication title -
indian journal of human genetics
Language(s) - English
Resource type - Journals
eISSN - 0971-6866
pISSN - 1998-362X
DOI - 10.4103/0971-6866.73410
Subject(s) - thalassemia , genetics , haplotype , hemoglobinopathy , compound heterozygosity , biology , allele , medicine , gene , disease
Sickle cell-β thalassemia (HbS-β thalassemia) is a sickling disorder of varying severity, which results from compound heterozygosity for sickle cell trait and β thalassemia trait. The present study was undertaken to determine the genetic factors responsible for the clinical variability of HbS-β thalassemia patients from western India.