Open AccessThe NQO1 allelic frequency in hindu population of central India varies from that of other Asian populations
Author(s) -
Sher Singh Parihar,
U.K. Chauhan
Publication year - 2010
Publication title -
indian journal of human genetics
Language(s) - English
Resource type - Journals
eISSN - 0971-6866
pISSN - 1998-362X
DOI - 10.4103/0971-6866.73403
Subject(s) - genotype , hardy–weinberg principle , allele , genetics , biology , genotype frequency , allele frequency , restriction fragment length polymorphism , polymorphism (computer science) , population , polymerase chain reaction , microbiology and biotechnology , gene , demography , sociology
THE ENZYMES ENCODED BY THE POLYMORPHIC GENES NAD (P) H: quinone oxidoreductase 1 (NQO1) play an important role in the activation and inactivation of xenobiotics. This enzyme has been associated with xenobiotic related diseases, such as cancer, therapeutic failure and abnormal effects of drugs.