Open AccessAmeliorative effects of operculina turpethum and its isolated stigma-5,22dien-3-o-β-D-glucopyranoside on the hematological parameters of male mice exposed to n-nitrosodimethylamine, a potent carcinogen
Author(s) -
Veena Sharma,
Manu Singh
Publication year - 2014
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.128789
Subject(s) - hemoglobin , pharmacology , n nitrosodimethylamine , white blood cell , red blood cell , blood cell , chemistry , carcinogen , medicine , immunology , biochemistry
Enormous propensity of plants to synthesize a variety of structurally diverse bioactive compounds, has made the plant kingdom a potential source of chemical constituents with various therapeutic values, including antitumor and cytotoxic activities. Blood is a good indicator to determine the physiological and pathological status of man and animal. The objective of the present study is to determine the effect of Operculina turpethum root extract and its isolated glycoside treatment on the hematological parameters in the mice with N-Nitrosodimethylamine (NDMA) induced cancer.