Open AccessPotentiation of the hepatic toxicity of carbon disulfide by chlordane
Author(s) -
Prasad S. Dalvi,
R. R. Dalvi,
Leonard H. Billups
Publication year - 2013
Publication title -
toxicology international/indian journal of toxicology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.129
H-Index - 26
eISSN - 0976-5131
pISSN - 0971-6580
DOI - 10.4103/0971-6580.117254
Subject(s) - glutathione , chemistry , lipid peroxidation , toxicity , microsome , carbon tetrachloride , medicine , endocrinology , alanine transaminase , corn oil , cytochrome , glutathione disulfide , cytochrome p450 , pharmacology , biochemistry , antioxidant , metabolism , in vitro , biology , enzyme , food science , organic chemistry
In this study, we investigated whether cytochrome P450s (CYPs) induced by a typical chlorinated hydrocarbon insecticide chlordane (CLD) potentiate hepatic toxicity of carbon disulfide (CS2).