Open AccessEffective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis
Author(s) -
Pavan Malleshappa,
Ravi Ramamurthi,
AP Chaudhari,
Preeti Singhai,
M Aghariya,
Abhinit Shah
Publication year - 2011
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.78077
Subject(s) - hemoperfusion , polymyxin b , septic shock , medicine , polymyxin , shock (circulatory) , antibiotics , intensive care medicine , sepsis , microbiology and biotechnology , hemodialysis , biology
Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India.