Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis | Zendy

Pavan Malleshappa | Zendy; Ravi Ranganath | Zendy; AP Chaudhari | Zendy; Preeti Singhai | Zendy; M Aghariya | Zendy; AB Shah | Zendy

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Effective use of polymyxin B hemoperfusion in septic shock complicated by urosepsis

Author(s) -

Pavan Malleshappa,

Ravi Ranganath,

AP Chaudhari,

Preeti Singhai,

M Aghariya,

AB Shah

Publication year - 2011

Publication title -

indian journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.317

H-Index - 24

eISSN - 1998-3662

pISSN - 0971-4065

DOI - 10.4103/0971-4065.78077

Subject(s) - hemoperfusion , polymyxin b , septic shock , medicine , polymyxin , shock (circulatory) , antibiotics , intensive care medicine , sepsis , microbiology and biotechnology , hemodialysis , biology

Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. Here we report one instance in which PMX-DHP therapy has been used successfully in a patient with septic shock from urosepsis. After antibiotic therapy, direct hemoperfusion using polymyxin B helped in cardiovascular stability. The patient recovered from the shock within a few days after treatment with polymyxin-B hemoperfusion. As far as we are aware, this is the first reported case of effective treatment of urosepsis complicated by septic shock using PMX-DHP therapy in India.

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