Open AccessLooking beyond the obvious: IgA nephropathy in a liver transplant recipient
Author(s) -
PM Kar,
Dongling Yi,
SM Kar
Publication year - 2010
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.65305
Subject(s) - medicine , hyaline , renal biopsy , nephropathy , biliary atresia , liver biopsy , renal transplant , biopsy , renal pathology , kidney , pathology , gastroenterology , liver transplantation , transplantation , endocrinology , diabetes mellitus
Seventeen years after a liver transplant for biliary atresia, an adolescent presented with renal failure. The serum level of cyclosporine was sub-therapeutic; and, in spite of dosage adjustments, the patient's status did not improve. Given the patient's age, future renal transplant was a feasible consideration. However, this warranted investigation in the form of a renal biopsy in an attempt to confirm the underlying cause(s) of her renal failure. The renal biopsy revealed marked alteration in the renal anatomy due to IgA deposition, interstitial fibrosis, and hyaline arteriopathy.