Open AccessCarotid intima-media thickness in patients with end-stage renal disease
Author(s) -
Kiran Kumar,
AY Lakshmi,
Pragna Rao,
Gaurav Chayan Das,
V Siva Kumar
Publication year - 2009
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.50674
Subject(s) - medicine , end stage renal disease , intima media thickness , disease , surrogate endpoint , dialysis , stage (stratigraphy) , cardiology , oxidative stress , ultrasonography , carotid ultrasonography , surgery , carotid arteries , paleontology , biology
Accelerated atherosclerosis and cardiovascular disease are major causes of morbidity and mortality in patients of end-stage renal disease. Carotid intima media thickness is taken as a useful surrogate marker of atherosclerosis. Thirty end-stage renal disease (ESRD) patients were subjected to ultrasonography to study CIMT before the initiation of dialysis. CIMT was found to be higher in ESRD patients than in controls. Levels of a serum marker of oxidative stress were also found to be higher in patients than in the controls. CIMT is an easy, noninvasive, reproducible, and cost-effective investigation in patients with chronic renal failure.