Open AccessEnd-stage renal disease in Tunisian infants: Etiology and outcome
Author(s) -
Manel Jellouli,
Abir Boussetta,
Kamel Abidi,
Yousra Hammi,
Chokri Zarrouk,
Tahar Gargah
Publication year - 2016
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.193753
Subject(s) - medicine , etiology , pediatrics , peritoneal dialysis , incidence (geometry) , end stage renal disease , disease , retrospective cohort study , urinary system , mortality rate , stage (stratigraphy) , dialysis , surgery , physics , optics , paleontology , biology
End stage renal disease (ESRD) in infants has particular features in terms of etiologies and therapeutic modalities. The aim of our study is to describe the etiologies and the ESRD outcomes among Tunisian infants. This retrospective study was conducted over 15 years (from January 1998 to December 31, 2013) in the Pediatric Department at Charles Nicolle Hospital. In total, 157 pediatric patients had ESRD. The mean incidence was 4.25 million children. The study involved 24 infants; the sex ratio was equal to 2. The mean age at diagnosis of ESRD was 8 months (range, 1-21 months). Growth retardation was noticed in 14 patients. The main causes were Congenital Anomalies of the Kidneys and Urinary Tract (9 infants) and hereditary renal disease (9 infants). All patients were treated with peritoneal dialysis; 16 infants presented peritonitis. Mortality rate was about 28%. The leading causes of death were cardiovascular diseases and infections.