Open AccessThrombotic microangiopathy: An unusual cause of renal failure in rheumatoid arthritis
Author(s) -
Ramanathan Sakthirajan,
J Dhanapriya,
Thanigachalam Dineshkumar,
Natarajan Gopalakrishnan,
S. Murugan,
T Balasubramaniyan
Publication year - 2017
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.179207
Subject(s) - medicine , thrombotic microangiopathy , microangiopathic hemolytic anemia , rheumatoid arthritis , plasmapheresis , oliguria , microangiopathy , hemodialysis , renal biopsy , gastroenterology , dermatology , biopsy , thrombotic thrombocytopenic purpura , disease , diabetes mellitus , immunology , renal function , platelet , endocrinology , antibody
Rheumatoid arthritis (RA) is one of the commonest rheumatological diseases. Renal involvement is not common but can occur as a result of chronic inflammation as part of disease process or drug toxicity. Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and organ failure of variable severity. Only a few cases of TMA in patients with RA were reported to date. We describe a 45-year-old female patient with RA who presented with oliguria and edema. Renal biopsy showed TMA with patchy cortical necrosis. She improved with hemodialysis and plasmapheresis.