Open AccessAcquired Bartter syndrome following gentamicin therapy
Author(s) -
J Singh,
Munna Lal Patel,
Kavya Gupta,
Sushil Pandey,
Anju Dinkar
Publication year - 2016
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.177206
Subject(s) - medicine , hypokalemia , polyuria , hypomagnesemia , metabolic alkalosis , bartter syndrome , gentamicin , fanconi syndrome , nephrotoxicity , distal renal tubular acidosis , aminoglycoside , hypercalciuria , renal tubular acidosis , urology , metabolic acidosis , endocrinology , acidosis , kidney , urinary system , antibiotics , diabetes mellitus , materials science , biology , microbiology and biotechnology , magnesium , metallurgy
Aminoglycoside nephrotoxicity may manifest as nonoliguric renal failure or tubular dysfunction, such as Fanconi-like syndrome, Bartter-like syndrome (BS), or distal renal tubular acidosis. We report a case who developed severe renal tubular dysfunction on the the 7 th day of gentamicin therapy, resulting in metabolic alkalosis, refractory hypokalemia, hypocalcemia, hypomagnesemia, and polyuria. The patient was diagnosed as a case of transient BS associated with gentamicin exposure. The patient recovered with conservative management.