Open AccessWarfarin related acute kidney injury: A case report
Author(s) -
Satish Mendonca,
Devika Gupta,
Arun Valsan,
Rohit Tewari
Publication year - 2017
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.177142
Subject(s) - medicine , warfarin , dabigatran , kidney disease , acute kidney injury , anticoagulant , renal function , nephropathy , kidney , prothrombin time , disease , atrial fibrillation , endocrinology , diabetes mellitus
Warfarin is an oral anticoagulant used extensively in clinical practice; However, its side-effect of causing renal damage has been recently detected. The mechanism leading to renal damage is glomerular hemorrhage and red blood cell tubular casts prothrombin time. Recently, it was found that warfarin causes renal damage in patients with chronic kidney disease and is also associated with progression of renal disease. Warfarin causing acute kidney injury in patients with normal renal function is a rare manifestation. It is important to be aware of this condition as its innocuous presence can lead to chronic kidney disease if not corrected in time. Further studies have also found that novel oral anticoagulants such as dabigatran also cause a similar syndrome and hence a new term called anticoagulant-related nephropathy is now in vogue.