Open AccessUnderstanding podocytopathy and its relevance to clinical nephrology
Author(s) -
Lavleen Singh,
Geetika Singh,
AK Dinda
Publication year - 2015
Publication title -
indian journal of nephrology/indian journal of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.317
H-Index - 24
eISSN - 1998-3662
pISSN - 0971-4065
DOI - 10.4103/0971-4065.134531
Subject(s) - medicine , focal segmental glomerulosclerosis , glomerulopathy , proteinuria , pathology , glomerulosclerosis , disease , intensive care medicine , kidney
Podocytopathies are the most common group of glomerular disorder leading to proteinuria. On the basis of pathophysiology, light microscopic and ultrastructural evaluation, the podocytopathies include minimal change disease, diffuse mesangial sclerosis, focal segmental glomerulosclerosis and collapsing glomerulopathy. The present review summarizes the basic etiopathogenesis of podocytopthies, highlights the common genetic and acquired factors in its causation, puts forth various diagnostic modalities and discusses the role of emerging agents or treatment.